18:00 - 20:00

Registration (Ballroom level)

20:00 - 22:00

Reception

7:00 - 8:00
7:30 - 17:00

Continental breakfast
Registration (continued)

Session 1
(8:00 - 10:00)

Chair: Mark Borodovsky, Georgia Tech

8:00 - 8:15

Don Giddens, Georgia Tech/Emory University
Welcome and Introduction

8:15 - 8:30

Peter Good, NIH
Genome Informatics program at the National Human Genome Research Institute

8:30 - 9:15

Chris Burge, MIT
Predicting splicing enhancers

9:15 - 10:00

Mark Gerstein, Yale University
Integrative genomics beyond the genes: computational analyses of pseudogenes and expression data

10:00 - 10:15

Coffee break

Session 2
(10:15 - 12:40)

Chair: Jim Fickett, Astra-Zeneca

10:15 - 11:00

Igor Zhulin , Georgia Tech
Can bioinformatics tackle signal transduction?

11:00 - 11:45

Milton Saier, University of California at San Diego
Genome archeology leading to the characterization and classification of transport proteins

11:45 - 11:55

Coffee break

11:55 - 12:40

Gary Stormo , Washington University
Probabilistic codes for DNA-protein interactions

12:40 - 14:00

Lunch in the Crown Room, on the top floor of the hotel

Session 3
(14:00 - 15:30)

Chair: Laurent Duret , Claude Bernard University

14:00 - 14:30

Artemis Hatzigeorgiou , University of Pennsylvania
DIANA-EST: a statistical analysis

14:30 - 15:00

Samuel Levy , Celera Genomics
Enrichment of regulatory signals in conserved non-coding genomic sequence

15:00 - 15:30

Zhiping Weng , Boston University
In silico prediction of the transcriptional regulation of human genes

15:30 - 15:50

Coffee break

Session 4
(15:50 - 17:20)

Chair: Gary Stormo , Washington University

15:50 - 16:35

Kenneth Wolfe, University of Dublin
The 2R hypothesis and the human genome sequence

16:35 - 17:20

Austin Hughes, University of South Carolina
Testing hypotheses of genome duplication

17:20 - 17:40

Coffee break

Poster session
(17:40 - 20:00)

Authors of posters with odd numbers are expected to be
next to their posters from 18:00 to 19:00.
Authors of posters with even numbers are expected to be
next to their posters from 19:00 to 20:00.

20:00

Dinner in the Crown Room, on the top floor of the hotel

7:00 - 8:00
7:30 - 17:00

Continental breakfast
Registration (continued)

Session 5
(8:30 - 10:00)

Chair: Kenneth Wolfe, University of Dublin

8:30 - 9:15

Nick Grishin, University of Texas Southwestern Medical Center
Remote homology detection and protein classification

9:15 - 10:00

Hanah Margalit, Hebrew University-Jerusalem
From database information to prediction of protein-DNA and protein-protein interaction

10:00 - 10:20

Coffee break

Session 6
(10:20 - 12:50)

Chair: Austin Hughes, University of South Carolina

10:20 - 11:05

Ewan Birney, EBI
Ensembl, annotation of large metazoan genomes

11:05 - 11:50

Chris Ponting, University of Oxford
The natural history of domains

11:50 - 12:05

Coffee break

12:05 - 12:50

Eugene Koonin, NCBI
Back to RNA world through comparative genomics

12:50 - 14:15

Lunch in the Crown Room, on the top floor of the hotel

Session 7
(14:15 - 15:45)

Chair: Hanah Margalit, Hebrew University, Jerusalem

14:15 - 14:45

King Jordan , NCBI
Genomic scale relative rates test and the detection of functional diversification among bacterial, archaeal and eukaryotic proteins

14:45- 15:15

Walter Ruzzo, University of Washington
Model-based clustering and data transformations for gene expression data

16:10 - 16:35

Rita Casadio, University of Bologna
Prediction of disulfide connectivity in proteins

15:45 - 16:00

Coffee break

Session 8
(16:00 - 17:30)

Chair: Arcady Mushegian, Stowers Institute for Medical Research

16:00 - 16:45

Luciano Brocchieri, Stanford University
Comparative analysis of protein lengths and amino acid usages among the three domains of life

16:45 - 17:30

Alexey Kondrashov, NCBI
A direct estimate of human per nucleotide spontaneous mutation rates at 20 loci causing Mendelian diseases

17:30 - 17:50

Coffee break

Poster session
(Continued)
(17:50 - 20:00)

Authors of posters with odd numbers are expected to be
next to their posters from 18:00 to 19:00.
Authors of posters with even numbers are expected to be
next to their posters from 19:00 to 20:00.

20:00

Dinner in the Crown Room, on the top floor of the hotel

7:30 - 8:30
7:30 - 8:30

Continental breakfast
Registration (continued)

Session 9
(8:30 - 9:30)

Chair: Chris Ponting, University of Oxford

8:30 - 9:00

Alexander Schliep, University of Cologne
Clustering protein sequences - structure prediction by transitive homology

9:00 - 9:45

Andrey Rzhetsky, Columbia University
Birth of scale-free molecular networks and the number of distinct DNA and protein domains per genome

9:45 - 10:00

Coffee break

Session 10
(10:00 - 11:45)

Chair: Eugene Koonin, NCBI

10:00 - 10:45

Laurent Duret, Claude Bernard University
Isochore organization of mammalian genomes: selection or neutral evolution?

10:45 - 11:30

John Logsdon, Emory University
Origin and evolution of meiosis: complex machinery of sex

11:30 - 11:45

Mark Borodovsky, Georgia Tech
Closing Remarks